publications

Peer-reviewed publications in reverse chronological order.

For the most up-to-date list, see my Google Scholar profile.

Journal articles

2025

  1. Comprehensive full-vessel segmentation and volumetric plaque quantification for intracoronary optical coherence tomography using deep learning
    Rick H J A Volleberg, Ruben G A Waerden, Thijs J Luttikholt, Joske L Zande, Pierandrea Cancian, Xiaojin Gu, Jan-Quinten Mol, Silvan Quax, and 9 more authors
    European Heart Journal - Digital Health, 2025
  2. World of Forms: Deformable geometric templates for one-shot surface meshing in coronary CT angiography
    Rudolf L M Herten, Ioannis Lagogiannis, Jelmer M Wolterink, Steffen Bruns, Eva R Meulendijks, Damini Dey, Joris R Groot, José P Henriques, and 3 more authors
    Medical Image Analysis, 2025
  3. Learning hemodynamic scalar fields on coronary artery meshes: A benchmark of geometric deep learning models
    Guido Nannini, Julian Suk, Patryk Rygiel, Simone Saitta, Luca Mariani, Riccardo Maragna, Andrea Baggiano, Gianluca Pontone, and 2 more authors
    Computers in Biology and Medicine, 2025
  4. Deployment of a digital twin using the coupled momentum method for fluid–structure interaction: A case study for aortic aneurysm
    Giacomo Creazzo, Guido Nannini, Simone Saitta, Davide Astori, Mario Gaudino, Leonard N Girardi, Jonathan W Weinsaft, and Alberto Redaelli
    Computers in Biology and Medicine, 2025
  5. Ascending aorta over-angulation is a risk factor for acute type A aortic dissection: evidence from advanced finite element simulations
    Ione Ianniruberto, Federica Lo Presti, Olimpia Bifulco, Davide Tondi, Simone Saitta, Davide Astori, Viviana L Galgano, Marisa De Feo, and 4 more authors
    European Journal of Cardio-Thoracic Surgery, 2025
  6. Automatic 4D mitral valve segmentation from transesophageal echocardiography: a semi-supervised learning approach
    Riccardo Munafò, Simone Saitta, Davide Tondi, Giacomo Ingallina, Paolo Denti, Francesco Maisano, Eustachio Agricola, and Emiliano Votta
    Medical & Biological Engineering & Computing, 2025

2024

  1. Implicit neural representations for unsupervised super-resolution and denoising of 4D flow MRI
    Simone Saitta, Marcello Carioni, Subhadip Mukherjee, Carola-Bibiane Schönlieb, and Alberto Redaelli
    Computer Methods and Programs in Biomedicine, 2024
  2. An automated and time-efficient framework for simulation of coronary blood flow under steady and pulsatile conditions
    Guido Nannini, Simone Saitta, Luca Mariani, Riccardo Maragna, Andrea Baggiano, Saima Mushtaq, Gianluca Pontone, and Alberto Redaelli
    Computer Methods and Programs in Biomedicine, 2024
  3. Left ventricle diastolic vortex ring characterization in ischemic cardiomyopathy: insight into atrio-ventricular interplay
    Alessandra Riva, Simone Saitta, Francesco Sturla, Giandomenico Disabato, Lara Tondi, Antonia Camporeale, Daniel Giese, Serenella Castelvecchio, and 4 more authors
    Medical & Biological Engineering & Computing, 2024
  4. Angulation and curvature of aortic landing zone affect implantation depth in transcatheter aortic valve implantation
    Riccardo Gorla, Omar A Oliva, Luca Arzuffi, Valentina Milani, Simone Saitta, Mattia Squillace, Enrico Poletti, Maurizio Tusa, and 5 more authors
    Scientific Reports, 2024
  5. A fully automated deep learning approach for coronary artery segmentation and comprehensive characterization
    Guido Nannini, Simone Saitta, Andrea Baggiano, Riccardo Maragna, Saima Mushtaq, Gianluca Pontone, and Alberto Redaelli
    APL Bioengineering, 2024
  6. A deep learning-based fully automated pipeline for regurgitant mitral valve anatomy analysis from 3D echocardiography
    Riccardo Munafò, Simone Saitta, Giacomo Ingallina, Paolo Denti, Francesco Maisano, Eustachio Agricola, Alberto Redaelli, and Emiliano Votta
    IEEE Access, 2024

2023

  1. A CT-based deep learning system for automatic assessment of aortic root morphology for TAVI planning
    Simone Saitta, Francesco Sturla, Riccardo Gorla, Omar A Oliva, Emiliano Votta, Francesco Bedogni, and Alberto Redaelli
    Computers in Biology and Medicine, 2023
  2. Data-driven generation of 4D velocity profiles in the aneurysmal ascending aorta
    Simone Saitta, Ludovica Maga, Chlöe Armour, Emiliano Votta, Declan P O’Regan, M Yousuf Salmasi, Thanos Athanasiou, Jonathan W Weinsaft, and 3 more authors
    Computer Methods and Programs in Biomedicine, 2023
  3. Quantification of paravalvular leaks associated with TAVI implants using 4D MRI in an aortic root phantom made possible by the use of 3D printing
    Philipp Aigner, Eleonora Sella Bart, Sebastiano Panfili, Tito Körner, Markus Mach, Martin Andreas, Markus Königshofer, Simone Saitta, and 3 more authors
    Frontiers in Cardiovascular Medicine, 2023

2022

  1. A deep learning-based and fully automated pipeline for thoracic aorta geometric analysis and planning for endovascular repair from computed tomography
    Simone Saitta, Francesco Sturla, Alessandro Caimi, Alessandra Riva, Maria Chiara Palumbo, Giovanni Nano, Emiliano Votta, Alessandro Della Corte, and 4 more authors
    Journal of Digital Imaging, 2022
  2. Comparison of four-dimensional magnetic resonance imaging analysis of left ventricular fluid dynamics and energetics in ischemic and restrictive cardiomyopathies
    Alessandra Riva, Francesco Sturla, Silvia Pica, Antonia Camporeale, Lara Tondi, Simone Saitta, Alessandro Caimi, Daniel Giese, and 7 more authors
    Journal of Magnetic Resonance Imaging, 2022
  3. Evaluation and verification of patient-specific modelling of type B aortic dissection
    Chlöe H Armour, Baolei Guo, Simone Saitta, Selene Pirola, Yifan Liu, Zhihui Dong, and Xiao Yun Xu
    Computers in Biology and Medicine, 2022
  4. The role of multiple re-entry tears in type B aortic dissection progression: a longitudinal study using a controlled swine model
    Chlöe Armour, Baolei Guo, Simone Saitta, Daqiao Guo, Yifan Liu, Weiguo Fu, Zhihui Dong, and Xiao Yun Xu
    Journal of Endovascular Therapy, 2022

2021

  1. Aortic hemodynamics assessment prior and after valve sparing reconstruction: A patient-specific 4D flow-based FSI model
    Guido Nannini, Alessandro Caimi, Maria Chiara Palumbo, Simone Saitta, Leonard N Girardi, Mario Gaudino, Mary J Roman, Jonathan W Weinsaft, and 1 more author
    Computers in Biology and Medicine, 2021
  2. Qualitative and quantitative assessments of blood flow on tears in type B aortic dissection with different morphologies
    Simone Saitta, Baolei Guo, Selene Pirola, Claudia Menichini, Daqiao Guo, Yan Shan, Zhihui Dong, Xiao Yun Xu, and 1 more author
    Frontiers in Bioengineering and Biotechnology, 2021
  3. The influence of inlet velocity profile on predicted flow in type B aortic dissection
    Chlöe Harriet Armour, Baolei Guo, Selene Pirola, Simone Saitta, Yifan Liu, Zhihui Dong, and Xiao Yun Xu
    Biomechanics and Modeling in Mechanobiology, 2021

2019

  1. Evaluation of 4D flow MRI-based non-invasive pressure assessment in aortic coarctations
    Simone Saitta, Selene Pirola, Filippo Piatti, Emiliano Votta, Federico Lucherini, Francesca Pluchinotta, Mario Carminati, Massimo Lombardi, and 5 more authors
    Journal of Biomechanics, 2019
  2. 4-D flow MRI-based computational analysis of blood flow in patient-specific aortic dissection
    Selene Pirola, Baolei Guo, Claudia Menichini, Simone Saitta, Weiguo Fu, Zhihui Dong, and Xiao Yun Xu
    IEEE Transactions on Biomedical Engineering, 2019

Preprints

  1. Pericoronary adipose tissue attenuation as a predictor of functional severity of coronary stenosis
    Marta Pillitteri, Guido Nannini, Simone Saitta, Luca Mariani, Riccardo Maragna, Andrea Baggiano, Gianluca Pontone, and Alberto Redaelli
    arXiv preprint arXiv:2502.13649, 2025
  2. MitraClip device automated localization in 3D transesophageal echocardiography via deep learning
    Riccardo Munafò, Simone Saitta, Luca Vicentini, Davide Tondi, Veronica Ruozzi, Francesco Sturla, Giacomo Ingallina, Andrea Guidotti, and 2 more authors
    arXiv preprint arXiv:2412.15013, 2024

Conference proceedings

2026

  1. Uncertainty analysis in intravascular OCT segmentation
    Leah Heil, Ruben G A Waerden, Rick H J A Volleberg, Jos Thannhauser, and Simone Saitta
    In IEEE International Symposium on Biomedical Imaging (ISBI), 2026

2025

  1. Attenuation artifact detection and severity classification in intracoronary OCT using mixed image representations
    Pierandrea Cancian, Simone Saitta, Xiaojin Gu, Rudolf L M Herten, Thijs J Luttikholt, Jos Thannhauser, Rick H J A Volleberg, Ruben G A Waerden, and 5 more authors
    In Medical Imaging 2025: Image Processing, 2025

2023

  1. Diastolic vortex ring derangements in ischemic cardiomyopathy left ventricles: a 4D Flow MRI study
    Alessandra Riva, Simone Saitta, Francesco Sturla, Antonia Camporeale, Lara Tondi, Silvia Pica, Daniel Giese, Serenella Castelvecchio, and 3 more authors
    In European Heart Journal – Cardiovascular Imaging, 2023

2022

  1. Mixed reality and deep learning for external ventricular drainage placement: a fast and automatic workflow for emergency treatments
    Maria Chiara Palumbo, Simone Saitta, Marco Schiariti, Maria Chiara Sbarra, Eleonora Turconi, Gabriella Raccuia, Junling Fu, Villiam Dallolio, and 3 more authors
    In Medical Image Computing and Computer Assisted Intervention – MICCAI 2022, 2022
  2. Fast automatic segmentation of mitral valve structures from 3D transesophageal echocardiography for transcatheter procedures: training and validation of a 3D U-Net convolutional neural network
    Simone Saitta, Riccardo Munafò, and Emiliano Votta
    In 8th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS), 2022

2021

  1. A deep learning-based and fully automated pipeline for thoracic aorta geometric analysis and TEVAR planning from computed tomography
    Simone Saitta, Francesco Sturla, Alessandro Caimi, Alessandra Riva, Maria Chiara Palumbo, Emiliano Votta, Alberto Redaelli, and Massimiliano M Marrocco-Trischitta
    In European Heart Journal – Cardiovascular Imaging, 2021
  2. Biomechanical impact of valve sparing procedure onto the native aorta: a multi-patient in silico study
    Valentina Scarponi, Alessandro Caimi, Simone Saitta, Maria Chiara Palumbo, Leonard N Girardi, Mario F Gaudino, Mary J Roman, Jiwon Kim, and 2 more authors
    In Circulation, 2021

2018

  1. Quantification of the aortic hemodynamics after transcatheter aortic valve implantation combining 3D-printing, 4D PC-MRI and computational fluid dynamics
    Selene Pirola, Francesco Sturla, Federico Lucherini, Riccardo Vismara, Michal Jaworek, Simone Saitta, Fabio Demarco, Francesca Pluchinotta, and 4 more authors
    In 8th World Congress of Biomechanics (WCB), 2018